BDBM25116 1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL306380::PP1::US10688093, Compound PP1 (Pfizer)::US10807986, Comparative compound 1::US11046696, Compound 1 of Comparative Examples::US11701353, PP1 (Pfizer)::cid_1400

SMILES Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C

InChI Key InChIKey=ZVPDNRVYHLRXLX-UHFFFAOYSA-N

Data  8 KI  34 IC50  1 EC50

PDB links: 5 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25116   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL

LigandBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)Copy SMILESCopy InChI

Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATPMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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